Quisinostat is a second-generation Histone Deacetylase Inhibitor (HDACi), a type of compounds, which interferes with the function of histone deacetylase. Histone deacetylases are molecules that remove acetyl groups from lysine residues resulting in condensed and transcriptionally inactive chromatin. The action of HDACi is the inhibition of tumour cells proliferation.
The Russian company will develop quisinostat together with the provision of R&D support to clinical trials. Janssen, in turn, will be responsible for expertise in external global clinical tests.
In a news release published on the company’s website Nikolay Savchuk, the Chairman of the Board of NewVac, says: “Our goal is to create an innovative world-class biomedical platform for the treatment of oncologic diseases based on molecularly targeted compounds including, but not limited to immunological cancer therapies in Russia”. “NewVac will initiate solid tumor combination therapy studies, which are accompanied by translational efforts. We are honored to commit our research organization to such a noble cause and we plan to start and conduct those clinical studies in Russia in 2013” – continues Savchuk.
Pharmaceutical industry in Russia is being influenced by government subsidies as well as thanks to the international cooperation. “Russia will develop the domestic pharmaceutical industry in order to decrease the country’s dependency on foreign medicines”, said President Dmitry Medvedev in 2010. In 2009 the Russian Ministry of Industry and Trade adopted a strategy called Pharma 2020. According to the policy, the government helps the local companies to increase the production of innovative medicines by covering the costs of R&D. One of the strategy’s objectives (which are planned to be attained by 2020) is to augment the share of locally produced medicines up to 50% on the internal market and to increase the pharmaceutical products export by eight times compared to 2008. It is assumed that the return of the investment should commence in 2017 principally through lower prices of domestically produced generics and innovative medicines purchase in the framework of public procurement.
The example of Janssen, as well as other foreign companies, shows that the Russian strategy provides favourable conditions to invest in Russia. If the goals of the Pharma 2020 are reached, Russian pharmaceutical industry will become a significant player on the international market.
Sources: http://www.healthcarepackaging.com
Pharma 2020 The Strategy of Development of the Pharmaceutical Industry of the Russian Federation - Analytical Summary - http://www.osec.ch
http://www.newvac.ru
Editor: Jakub Chrustowicz
Guest
2021-06-08 21:21:57 +0200
Yes it is true that Dr Isikolo is the best to restore broken homes and relationships. My name is Jojo Ivan and i was a client for DR ISIKOLO and i must tell you that he is a real spell caster. When i contacted this spell caster my boyfriend had left me for 2 years and i have always wanted him back to me. I contacted DR ISIKOLO to help me about a two weeks ago and i have reconnected with my boyfriend. When my ex boyfriend left me it was turmoil for me. This became a disaster for me that i had a physiological trauma and my family were very worried about my health. After 2 years, I met DR ISIKOLO through a testimony also and he told me to calm myself that no matter what the problem is, he is well and ready to help anyone who comes to him. Just in 2 days, my ex called me and wanted to meet. I agreed and made preparations to meet him and he told me how he had felt guilty for what he did and he wanted me back. I praised DR ISIKOLO for his marvelous handiwork and i will recommend him to anyone who needs a spell caster. Contact him to help you and fast at his email: isikolosolutionhome@gmail.com You can also WhatsApp him on +1(725)240-4536
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Guest
2021-05-20 04:00:16 +0200
Am here to testify what this great spell caster done for me. i never believe in spell casting, until when i was was tempted to try it. i and my wife have been having a lot of problem living together, she will always not make me happy because she have fallen in love with another man outside our relationship, i tried my best to make sure that my wife leave this woman but the more i talk to her the more she makes me fell sad, so my marriage is now leading to divorce because she no longer gives me attention. so with all this pain and agony, i decided to contact this spell caster to see if things can work out between me and my wife again. this spell caster who was a man told me that my wife is really under a great spell that she have been charm by some magic, so he told me that he was going to make all things normal back. he did the spell on my wife and after 5 days my wife changed completely she even apologize with the way she treated me that she was not her self, i really thank this man his name is Dr ose he have bring back my wife back to me i want you all to contact him who are having any problem related to marriage issue and relationship problem he will solve it for you. his email is oseremenspelltemple@gmail.com he is a man and his great. wish you good time.
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Guest
2021-05-03 06:05:31 +0200
Thank you so much DOCTOR ISIKOLO for making my ex boyfriend come back to me. I am writing this wonderful testimony in respect of this man. He made all my wishes come true. My boyfriend and i dated for more than 3 years and although we had had so many quarrels but we never thought of a break up. One day, he called me over the phone telling me how he is tired of the relationship and cannot see anywhere that we are heading to. Months have passed and my boyfriend did not contact me anymore and i did not hear from him anymore and his cell phone was disconnected. I knew i need to seek for help because of the so much love i have for him. I contacted this great spell caster because i have never contacted anyone before and i tell you that after a 2 days of contact, my ex boyfriend called me and asked to see me and the next morning, he wore a ring on my finger. I am very happy because i am soon going to be a married woman with the help of this great spell caster called DOCTOR ISIKOLO. I promised to manifest your works to everyone and please contact this man to help you at isikolosolutionhome@gmail.com or his WhatsApp him on: +2348133261196.
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2021-04-29 21:09:39 +0200
Five weeks ago my boyfriend broke up with me. It all started when i went to summer camp i was trying to contact him but it was not going through. So when I came back from camp I saw him with a young lady kissing in his bed room, I was frustrated and it gave me a sleepless night. I thought he will come back to apologies but he didn't come for almost three week i was really hurt but i thank Dr.Azuka for all he did i met Dr.Azuka during my search at the internet i decided to contact him on his email dr.azukasolutionhome@gmail.com he brought my boyfriend back to me just within 48 hours i am really happy. What’s app contact : +44 7520 636249
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2021-04-14 04:21:10 +0200
I want to thank Dr. Emu for getting my lover back to me within 48 hours. When my lover left me i was so tired and frustrated till i search the internet for help and i saw so many good talk about Dr Emu and i decided to give him a try and i contact him and explain my problems to him and he cast a love spell for me which i use to get my husband back. If you want to get your lover back contact Dr Emu via email: emutemple@gmail.com Dr Emu the great man that is able to bring back lost love
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2021-02-09 18:45:48 +0100
DR ISIKOLO has done it again for me after helping me to get my husband back. i want to let the world know about DR ISIKOLO the Great spell caster that brought back my estranded husband to me when i thought all hope was lost. so i contacted him and complied with all he told me to do and indeed, i got the result in 48 hours as he assured me. DR ISIKOLO used his powerful spell to put a smile on my face by bring back my man with his spell, at first i thought i was dreaming when my husband came back to me on her knees begging me to forgive her and accept her back and even since then he loves me more than i ever expected so i made a vow to my self that i will let the World know about DR ISIKOLO because he is a great man. Do you have problems in your relationship? have your partner broke up with you and you still love and want him or her back? Do you have problem with your finance ? or do you need help of any kind then contact DR ISIKOLO today for i give you 100% guarantee that he will help you just as he helped me. DR ISIKOLO email address is: isikolosolutionhome@gmail.com.com or his WhatsApp/Viber him on: +2348133261196.
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Guest
2020-05-27 04:59:32 +0200
Its a pleasure for me to write this testimony about how i got my Ex Husband a month ago. i have been reading so many good comments of some people who were help by Dr Adoda which i believe . I was hurt and depressed, I was too curious and wanted to try Dr.Adoda when i had issues with my husband, then i contacted him through his website (http://dradodalovetemple.com) when i contact him, he assured me 100% that he will bring him back, i pleaded with him to help me out. to My greatest suprise he did a successful love spell for me, and require me to do something which i agreed with him. To my greatest surprise i got a good result after 48hours i contacted him, i am really happy that i am with my ex husband again. I have waited for 2years to be with him again. So i guess its time i recommend anyone going through Relationship/ marriage problems should reach him through his Email ( adodalovespelltemple440@gmail.com ) OR add him on whatsapp +2348112825421.
visit his Youtube page to watch testimony on ( https://youtu.be/B279mkEo_C4 )
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2020-05-24 16:17:43 +0200
My name is Amelia. from Canada. Am here to testify of a great and powerful spell caster named Dr.Adoda I was so confused and devastated when my lover left me for another girl. I needed him back desperately because i loved him so much. So i contacted this great spell caster on (adodalovespelltemple440@gmail.com ) for help. He helped me cast a return love spell on my boyfriend and just within 48hours my boyfriend came back to me crying and begging for my forgiveness. Dr. Adoda released him to know how much i loved and wanted him back. And He also opened his eyes to picture how much love we have share together. As I am writing this testimony right now i am the most happiest woman on earth. I want to recommend this great spell caster to anyone that truly needs an urgent solution to a love break up Email him at; adodalovespelltemple440@gmail.com or What-App his call phone number on +2348112825421.
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Guest
2020-05-19 08:37:12 +0200
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i am here to give testimony on how this powerful spell caster called Dr Adoda helped me to fix my relationship. i was heartbroken when my fiancee told me he is no longer interested in marrying me because he was having an affair with the other woman where he work. I cried and sobbed every day, until it got so bad that I reached out to the Internet for help, that was when i read a review about the great work of Dr Adoda, then i contacted him for help to get my lover back, he helped me cast a powerful (reconciliation love spell) and to my greatest surprise after 48 hours of doing the love spell my Fiancee came back on his knees begging me to forgive him We are now happily married and all thanks goes to Dr Adoda Wonders for helping me save my relationship you can contact Dr Adoda through his email address: adodalovespelltemple440@gmail.com or WHATSAPP him on +2348112825421.
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Guest
2020-05-15 15:02:40 +0200
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i am here to give testimony on how this powerful spell caster called Dr Adoda helped me to fix my relationship. i was heartbroken when my fiancee told me he is no longer interested in marrying me because he was having an affair with the other woman where he work. I cried and sobbed every day, until it got so bad that I reached out to the Internet for help, that was when i read a review about the great work of Dr Adoda, then i contacted him for help to get my lover back, he helped me cast a powerful (reconciliation love spell) and to my greatest surprise after 48 hours of doing the love spell my Fiancee came back on his knees begging me to forgive him We are now happily married and all thanks goes to Dr Adoda Wonders for helping me save my relationship you can contact Dr Adoda through his email address: adodalovespelltemple440@gmail.com or WHATSAPP him on +2348112825421.
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Guest
2018-11-24 19:30:19 +0100
I am Neri Juan and This is the case of My boyfriend of two years left me for another girl because I accuse him of seeing another girl and since then i have been trying to get him but he refuse to come back to me, he was not responding to my call or email and he even unfriend me on face-book and he told me that he is done with me. i was searching on the internet for help and i saw a testimony of how a spell caster help them to get their ex back so i decided to give it a try and i contacted him and i explain my problems to him and he cast a love spell for me and guarantee me of 3days that my ex will come back to me and to my greatest surprise the third day a great miracle fell on me and my ex come back to me on the third day and he beg me for forgiveness. i will continue to publish his name because he is my Savior and we are happily married now. If you need him to help you Email isikolosolutionhome@gmail.com. call or Whatsapp him on +2348133261196
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Guest
2018-09-10 07:23:35 +0200
BEST ONLINE LOVE SPELL CASTER TO GET YOUR EX LOVER, HUSBAND, WIFE, GIRLFRIEND OR BOYFRIEND BACK. ADD HIM UP ON WHATSAPP: +2348104557346 or +2347055064262
Hello my respectable viewers, Am Roseline Carter and i'm from FLORIDA, UNITED STATE I am very happy to share this amazing testimony, i was hurt and heart broken when my husband left me with our kid, i was confused and didn't know what to do, i loved him so much, i tried all i could to bring him back but all my effort was in vain , on one faithful day i explained my problem to my friend, and she told me of a great love spell caster called "DR KEN" whom also make her pregnant when she was looking for a child, i never believed in spells but i just have to give it a try to see if things will get better, i contacted DR KEN through the contact info my friend gave to me, after some hours the spell caster responded to me he told me to stay and gave me some instructions on what to do and i did exactly as i was told, to my greatest surprise, my husband who has not called me for a very long time , called me and start apologizing for all the wrongs he did to me and pleaded with me that he want to return home to me and the kids, now he loves me more than ever before, my respectable viewers,brothers and sisters if you are passing through any kind of problem contact him and i give you 100% guarantee that he will solve your problems.
His email address is : greatdrkenspelltemple@gmail.com
or you can add him up on whatsApp via his cellphone numbers: +2348104557346 or +2347055064262
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Guest
2016-09-21 19:35:52 +0200
Testimony On How My Ex Come Back
Jessica by name and i am located in USA ,I recently saw a testimony about a spell caster of some sort in a blog I visit for relationship and dating counseling problems because i had been having serious problems with my boyfriend and we had been dating for 2 year, He just suddenly changed, He wasn’t returning my calls, He started cheating, He was hurting me in so many ways i never thought possible and I just thought I should try this spell caster called Dr.Mako Cos there are so many good comments about him on the website, But before i could read his post,I have already contacted many spell caster that cheated me out of my hard earned money without given me result.But when i meet this spell caster out of desperation of some sort.I decided to contact them to please render there help to me, I explained all the problems that i was going through to him and he told me all i needed to do to get this spell castes. At first everything felt dreamy and unbelievable, Their consultations and solution was a little bit easy and strange and I was scared a little cos I had read and heard lots of stories of fake spell casters, scams and i never really believed in magic. I played along with a little hope and faith and I was sent some few stuffs after everything and it worked like a miracle, everything went to a whole new direction, it was and is amazing. I guess it was all good faith that made me read That particular post that faithful day.I hope he could help other people too like he did to me. I did a little and I got everything I wanted and wished for, My boyfriend, My family and my life back You can contact Dr.Mako at: Makospelltemple@yahoo.com because he changed my life call him on +2347054263874
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Guest
2016-09-21 19:35:41 +0200
Testimony On How My Ex Come Back
Jessica by name and i am located in USA ,I recently saw a testimony about a spell caster of some sort in a blog I visit for relationship and dating counseling problems because i had been having serious problems with my boyfriend and we had been dating for 2 year, He just suddenly changed, He wasn’t returning my calls, He started cheating, He was hurting me in so many ways i never thought possible and I just thought I should try this spell caster called Dr.Mako Cos there are so many good comments about him on the website, But before i could read his post,I have already contacted many spell caster that cheated me out of my hard earned money without given me result.But when i meet this spell caster out of desperation of some sort.I decided to contact them to please render there help to me, I explained all the problems that i was going through to him and he told me all i needed to do to get this spell castes. At first everything felt dreamy and unbelievable, Their consultations and solution was a little bit easy and strange and I was scared a little cos I had read and heard lots of stories of fake spell casters, scams and i never really believed in magic. I played along with a little hope and faith and I was sent some few stuffs after everything and it worked like a miracle, everything went to a whole new direction, it was and is amazing. I guess it was all good faith that made me read That particular post that faithful day.I hope he could help other people too like he did to me. I did a little and I got everything I wanted and wished for, My boyfriend, My family and my life back You can contact Dr.Mako at: Makospelltemple@yahoo.com because he changed my life call him on +2347054263874
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Guest
2016-09-09 01:19:15 +0200
Hello every body my name is Synder Anderson I just want to share my experience with the world on how Lord Alika help me, I got my love back and saved my marriage… I was married for 3 years with 1 kid and we lived happily until things started getting ugly and we had fights and argued almost e very time… it got worse at a point that he filed for divorce I tried my best to make him change his mind & stay with me because I love him so much and don’t want to lose him but everything just didn’t work out… he moved out of the house because it was a rented apartment and still went ahead to file for divorce… I pleaded and tried everything but still nothing worked. The breakthrough came when someone introduced me to this wonderful, great spell caster who eventually helped me out… I have never been a fan of things like this but just decided to try reluctantly because I was desperate and left with no choice… He did special prayers and used his power… Within 4 days my husband called me and he said he was sorry for all the emotional pains he had cost me, moved back to the house and we continue to live happily and our kid is happy too and we are expecting our second child… and my Husband also got a new job and our lives became much better web:http://lordalikaspelltemp8.wix.com/http I have introduced him to a lot of couples with problems across the world and they have had good news..contact him on lordalikaspelltemple@yahoo.co.uk or +19206246318. web:http://lordalikaspelltemp8.wix.com/http
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Guest
2016-04-03 06:22:48 +0200
My name is Jessica Luis, and I base in USA...My life is back!!! After 1 years of Broken marriage, my husband left me with two kids . I felt like my life was about to end i almost committed suicide, i was emotionally down for a very long time. Thanks to a spell caster called Dr Mohammed, which i met online. On one faithful day, as I was browsing through the internet,I came across allot of testimonies about this particular spell caster. Some people testified that he brought their Ex lover back, some testified that he restores womb,cure cancer,and other sickness, some testified that he can cast a spell to stop divorce and so on. i also come across one particular testimony,it was about a woman called Sonia,she testified about how he brought back her Ex lover in less than 2 days, and at the end of her testimony she dropped Dr Mohammed's e-mail address. After reading all these,I decided to give it a try. I contacted him via email and explained my problem to him. In just 48hours, my husband came back to me. We solved our issues, and we are even happier than before Dr Mohammed, is really a gifted man and i will not stop publishing him because he is a wonderful man... If you have a problem and you are looking for a real and genuine spell caster to solve all your problems for you. Try High monicaspiritualtemple@gmail.com anytime, he might be the answer to your problems. Here's his contact: monicaspiritualtemple@gmail.com or call him +2348134493948
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Guest
2016-04-03 04:11:35 +0200
'After being in relationship with Wilson for seven years,he broke up with me, I did everything possible to bring him back but all was in vain, I wanted him back so much because of the love I have for him, I begged him with everything, I made promises but he refused. I explained my problem to someone online and she suggested that I should contact a spell caster that could help me cast a spell to bring him back but I am the type that don't believed in spell, I had no choice than to try it, I meant a spell caster called Dr Zuma zuk and I email him, and he told me there was no problem that everything will be okay before three days, that my ex will return to me before three days, he cast the spell and surprisingly in the second day, it was around 4pm. My ex called me, I was so surprised, I answered the call and all he said was that he was so sorry for everything that happened, that he wanted me to return to him, that he loves me so much. I was so happy and went to him, that was how we started living together happily again. Since then, I have made promise that anybody I know that have a relationship problem, I would be of help to such person by referring him or her to the only real and powerful spell caster who helped me with my own problem and who is different from all the fake ones out there. Anybody could need the help of the spell caster, his email: spiritualherbalisthealing@gmail.com or call him +2349055637784 you can email him if you need his assistance in your relationship or anything. CONTACT HIM NOW FOR SOLUTION TO ALL YOUR PROBLEMS'
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Guest
2016-04-02 05:14:50 +0200
My husband and I have been married for about 7 yrs now. We were happily married with two kids, a boy and a girl. 3 months ago, I started to notice some strange behavior from him and a few weeks later I found out that my husband is seeing someone. He started coming home late from work, he hardly care about me or the kids anymore, Sometimes he goes out and doesn't even come back home for about 2-3 days. I did all I could to rectify this problem but all to no avail. I became very worried and needed help. As I was browsing through the internet one day, I came across a website that suggested that Dr Unity can help solve marital problems, restore broken relationships and so on. So, I felt I should give him a try. I contacted him and he did a spell for me. Three days later, my husband came to me and apologized for the wrongs he did and promise never to do it again. Ever since then, everything has returned back to normal. I and my family are living together happily again.. All thanks to Dr Unity . If you need a spell caster that can cast a spell that truly works, I suggest you contact him. He will not disappoint you. This is his E-mail: Unityspelltemple@gmail.com .
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