Around 45% people suffering from leukaemia survive at least four years after the diagnosis. This number has tripled in the last forty years, but the recent breakthroughs of Czech scientists give a positive prospect for the future of leukaemia treatment. In September 2012 the research team from the Institute of Pathological Physiology of the 1st Medicine Faculty at Prague’s Charles University discovered that stem cells can be transplanted to people suffering from blood formation diseases even several hours after the donor’s death. Thanks to this finding, the number of bone marrow donors will be increased. It is especially good news since a very high level of immunogenetic congruence between the donor and the recipient is needed to perform transplantation and that is why the chances to find a suitable donor are significantly lessened. The Czech research team proved for the first time that “unlike other cells, stem cells taken even a number of hours after death fully preserve their natural qualities, and consequently they are suitable for transplant,” as Professor Necas said.
In February 2013 the next discovery of Czech scientists from the Institute of Molecular Genetics, this time, was announced. The researchers described so far unknown mechanism of how the malignant cells penetrate the bone marrow and enter the blood cells during acute myeloid leukaemia. The institute's head, Vaclav Horejsi, said: "Leukaemic cells kill the surrounding cells, thereby they create a certain canal and bite through to the blood where they start spreading in the whole body”.
The recent discoveries constitute a positive sign for the patients suffering from leukaemia and their practical application is only the matter of time.
by Jakub Chrustowicz
2018-10-08 14:59:27 +0200
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