Unlike other specimens relying on hemoglobin, the Transylvanian blood is based on hemerythrin – a protein extracted from sea worms. Mixed with water and salts is able of oxygen transporting and can be used in reducing infection rates during blood donation.
Hemerythrin was found as a better base for blood substitute than hemoglobin due to its better resistance to physical and chemical stress occurring in an organism. In the previous trials, nonresistant hemoglobin-based artificial blood would produce toxic byproducts.
Further preclinical tests on animals and cell cultures will be performed in the nearest future. The proper clinical trials will take place in 2016-2017 and will last next 2-3 years. Supposing the tests will give positive results, our artificial blood would be applied in hospitals as a real blood substitute - says Dr. Radu Silaghi-Dumitrescu.
The scientist claims that large-scale production of this substance is possible and could be as popular in the future as insulin is today.
The artificial blood synthesis is very important aspect of research. According to the Regional Blood Center in Lodz the blood assets are insufficient, especially those with Rh- factor.
Apart from the Fluosol-DA-20, withdrawn from usage in 1994 due to its side effects, there were no blood substitutes on the world’s market to date. That is due to the requirements that must be fulfilled. Such product must be nontoxic, stable, cheap to synthesize and it must not interact with oxygen.
The success of Transylvanian scientists is a real milestone in the development of artificial blood. However, there is still a long way before them and the success is really uncertain.
by Piotr Kołata
2018-09-10 07:46:19 +0200
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