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Treatment tailored to the patient – the world of personalized medicine

Treatment tailored to the patient – the world of personalized medicine

Publish date: 2012-03-12

We are all alike – one could say when it comes to general features of people all around the world. Our general appearance, physical and psychological needs are very similar. Yet, “similar” does not mean “the same”. This fact is particularly important in terms of healthcare, where the issue of difference led to formation of a revolutionary branch of science called “personalized medicine”.

Tags: medicine , pharma

According to the Personalized Medicine Coalition (PMC), this term may be defined as “tailoring of medical treatment to the individual characteristics of each patient”. Thanks to this approach the problem of different response of patients to disease treatment may be overcome.

Targeted healthcare implies successful treatment for many conditions, such as different forms of cancer, multiple sclerosis, most of metabolic diseases, or even HIV. It is based on specific molecular diagnostics of a patient, which allows estimation of the disease source and monitoring of its treatment results. Even though molecular diagnostics has been known for years, its recent rapid development is directly connected to progress in science and technology emerging from academics and companies.

Many drug firms and corporations may list their achievements in personalized healthcare. For instance, Herceptin – one of the most potent examples of practical personalized medicine launched by Roche and Genentech– is highly efficient against breast cancer. Yet, only one in five patients responds to the treatment due to possession of a specific gene polymorphism (variation). It proves its great dependence on molecular diagnostics seeking for specific biomarkers, which inform whether the available drug is suitable for the patient or not. If not, then the challenge is to design a proper one. It is faced by all the top personalized drug companies in the world. Exemplifying, Novartis aims to deliver complete diagnostic services to the market based on “deep understanding of diseases and clinical needs”, which leads to delivering the right drug to the right patient at the right time.

Innovative medical treatment always needs some time for adoption. An ordinary European hospital is usually not adjusted to run advanced molecular research. This problem has been solved recently by Genomed, a Polish company dealing with molecular diagnostics, which runs its own genetic clinic in parallel to DNA analysis and synthesis for the biotechnology market.

By contrast, Biocartis, famous company founded by Rudi Pauwels, fosters molecular diagnostics comparable to handling of a coffee maker. The idea is to create miniaturized equipment for multiplexed and fast diagnostics at low cost and reliable level, possible to be handled without specific training. The invention would increase access to molecular diagnosis and dramatically lower its costs. This would be beneficial for all recipients: patients, hospitals, clinics and molecular diagnostics companies as well.

Present situation of the market of personalized medicine has reached just a tip of the iceberg. There are obstacles to overcome all around the world, such as specific environments, different investment systems, popular one-size-fits-all treatment model, and above all – mutual assistance. As indicated by Edward Abrahams, the president of PMC, the key for successful adoption of personalized medicine inventions together with development of respective companies in the market is cooperation: “It requires science and technology to be developed to understand how patients respond differently, (…) the regulatory environment that is conducive the development of products, which are targeted to individuals, (…) systems of payment that will pay for these products and also finally requires physicians and other providers to understand and adopt those products when they are available”. The PMC is one of the international organizations which unite representants of all the stated business areas and other interested entities, like direct recipients of personalized products and methods. The goal is to support business collaboration between current market drivers to allow development of medical prospects and treatment quality through mutual education and promotion of new possibilities in healthcare. “Our mission is to focus on the patient”, says Edward Abrahams.

What about the future of personalized medicine? There is a general agreement on that sooner or later targeted healthcare will dominate the world market. Potential recipients of the products and methods are everyone and the goal is to make personalized treatment available to them. “Everyone” means not only those from the area of emerging technologies but also countries of lower income where the medical needs are great, as said by Francis S. Collins, the director of the National Institutes of Health (NIH). Increasing knowledge concerning genetic profiles of patients will lead not only to improved treatment of existing diseases but above all to their successful prevention. We will keep our fingers crossed for the development of the global personalized healthcare market.

Anna Drzazga

 

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2021-01-12 10:02:07 +0100
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2020-02-29 02:02:48 +0100
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2020-01-23 17:13:37 +0100
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2020-01-07 04:42:04 +0100
How i got back my ex husband after he left me and our kids” I suggest you read my testimony. I'm Tracy Mattingly from united state, I'm so excited my husband is back after he left me for another woman. My husband was having an affair with a co-worker and i love my husband so much but he was cheating on me with his co-worker and this girl i think use witchcraft or black magic on my husband to make him hate me and this was so critical and uncalled-for, I cry all day and night for God to send me a helper to bring back my husband! I was really upset and i needed help, so i searched for help online and I came across a website that suggested that Dr Unity can help get ex-boyfriend back fast. So, I felt I should give him a try. I contacted him and he told me what to do and i did it, then he did a love spell for me. 11hours later, my husband really called me and told me that he miss me so much, Oh My God! i was so happy, and today i am happy with my man again and we are joyfully living together and i thank the powerful spell caster Dr.Unity, he is so powerful and i decided to share my story on the here. if you are here and your Lover is turning you down, or your husband moved to another woman, do not cry anymore, contact Dr.Unity for help now..Here’s his contact Email him at: Unityspelltemple@gmail.com or Call/Whats-app: +2348055361568 ,website:https://drunity.simplesite.com
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2020-01-05 07:55:12 +0100
How i got back my ex husband after he left me and our kids” I suggest you read my testimony. I'm Tracy Mattingly from united state, I'm so excited my husband is back after he left me for another woman. My husband was having an affair with a co-worker and i love my husband so much but he was cheating on me with his co-worker and this girl i think use witchcraft or black magic on my husband to make him hate me and this was so critical and uncalled-for, I cry all day and night for God to send me a helper to bring back my husband! I was really upset and i needed help, so i searched for help online and I came across a website that