10 years ago a Nobel Prize awarded a discovery connecting Helycobacter pylori with gastric carcinogenesis. But only today, a host-microbiome relation research starts to enter its critical phase. It turns out, that we are not the only architects of our own fortune – they are, small frequenters of our ...
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Collaboration spans the discovery, development and commercialization of cancer vaccines and other cancer immunotherapies in gastric, lung and prostate cancer
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Synektik Group - a leading provider of innovative products, services and IT solutions for diagnostic imaging and nuclear medicine - begins delivery of a special radiotracer, IASOcholine, to the Czech Republic and Slovakia. PET-CT imaging using Choline radiotracer is one of the most modern methods use...
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Novartis drug “Jakavi” has been approved by the European Commission for the therapy of rare blood cancer, polycythemia vera. It is the first approved targeted drug for treatment of this disease and it gives hope for patients unresponsive to standard therapy with hydroxyurea....
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Wortmannin sensitize the tumour cells for standard treatment with ethoposid and cisplatin, makes the treatment more effectiveness. What it means for the glioma patient? That there is potential new drug, which is effective in laboratory and kills glioma cells....
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Interactions between cells are of crucial importance for the proper functioning of tissues and the whole multicellular organisms. During pathological processes, such as cancer progression, alterations in cell-cell adhesion are very common. The molecular events underlying these changes must be deeply ...
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Life science sector comprising such areas as biotechnology, pharmacy or biomedical technologies is one of the most rapidly growing markets. As societies all over the world are getting older and older, we can be sure that in the nearest 15 years its development will be even faster than nowadays....
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Angiogenesis, comprising a growth of blood vessels, is indispensable for proper organ functioning and repair. Abnormalities occurring in this crucial process are involved in various disorders such as cancer. Understanding its molecular background is the basis for the development of novel efficient dr...
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Nucleolin, a multifunctional phosphoprotein present mainly in nucleolus, has drawn much attention of molecular biologists due to its role in carcinogenesis and potential of being attractive target for more efficient therapies. As current methods of cancer treatment are still highly unspecific, such a...
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European Commission (EC) approved the bevacizumab (Avastin) as a medication in treating recurrent ovarian cancer resistant to chemotherapy containing platinum. Avastin has to be combined with paclitaxel, topotecan, or pegylated liposomal doxorubicin chemotherapy....
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Common cat parasite which is harmful and sometimes deadly to people can be transformed into anticancer vaccine. Tumors disturbed natural immune response in order to be safe against natural forces defense of the body. While T. gondii is presence in cells, they started to produce toxic lymphocytes T an...
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One of the most commonly worldwide consumed beverages is tea. Still black tea is consumed most frequently, however, the green tea contains majority of natural bio-active chemicals beneficial for our health. Epigallocatechin-3-gallate (EGCG) is an active compound of green tea that was used in studies ...
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Merck, one of the leaders in production of pharmaceuticals, put its new medicine under review. It is called vintafolide, MK-8109 and it is an injectable drug conjugate consisting of folate (vitamin B9) linked to alkaloid chemotherapy agent, desacetylvinblastine monohydrazine (DAVLBH). ...
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On 1 November 2013, Genentech announced that the U.S. Food and Drug Administration (FDA) approved Gazyva (obinutuzumab) to be used with chlorambucil chemotherapy for the treatment of chronic lymphocytic leukemia (CLL). ...
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Darmstadt, Germany, October 24, 2013 – Merck Serono, the biopharmaceutical division of Merck, and Selvita, a biotechnology company based in Poland, announced today that they have entered into a collaboration to jointly discover small molecule based drugs targeting proteins involved in cancer cell met...
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Researchers at Johns Hopkins University have identified a gene which repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tubers to enlarge and spread to distant sites. The researchers hope that this so-called "master regulator” gene may be the key to develop a new...
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